UVB-induced mutagenesis in hairless lambda lacZ-transgenic mice.

doi:10.1002/(sici)1098-2280(1997)29:2<136::aid-em4>3.0.co;2-c

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Article

UVB-induced mutagenesis in hairless lambda lacZ-transgenic mice.

Environmental and molecular mutagenesis - 1 Jan 1997

Frijhoff A F, Rebel H, Mientjes E J, Kelders M C, Steenwinkel M J, Baan R A, van Zeeland A A, Roza L

Abstract excerpt

UVB-induced mutagenesis was studied in hairless 40.6 transgenic mice (MutaMouse), which contain the lambda gt10lacZ shuttle vector as a target for mutagenesis. Mice were exposed at the dorsal side to either single doses of 200, 500, 800, or 1000 J/m2 UVB or to two successive irradiations of eithe...

Topics

Animals
Lac Operon
Mice
Mice, Transgenic
Mutagenesis
Mutation
Sequence Analysis, DNA
Ultraviolet Rays

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