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Article

The 'polysemous' codon--a codon with multiple amino acid assignment caused by dual specificity of tRNA identity.

The EMBO journal - 3 Mar 1997

Suzuki T, Ueda T, Watanabe K

Abstract excerpt

In some Candida species, the universal CUG leucine codon is translated as serine. However, in most cases, the serine tRNAs responsible for this non-universal decoding (tRNA(Ser)CAG) accept in vitro not only serine, but also, to some extent, leucine. Nucleotide replacement experiments indicated that m1G37 is critical for leucylation activity. This finding was supported by the fact that the tRNA(Ser)CAGs possessing...

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Identifiers

PMID: 9118950
DOI: 10.1093/emboj/16.5.1122
PMCID: PMC1169711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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