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Article

Candida albicans CUG Mistranslation Is a Mechanism To Create Cell Surface Variation

26 Jun 2013

Abstract excerpt

UNLABELLED: In the human fungal pathogen Candida albicans, the CUG codon is translated 97% of the time as serine and 3% of the time as leucine, which potentially originates an array of proteins resulting from the translation of a single gene. Genes encoding cell surface proteins are enriched in CUG codons; thus, CUG mistranslation may influence the interactions of the organism with the host. To investigate this,...

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PMID: 23800396
DOI: 10.1128/mbio.00285-13

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