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Article

Obesity is associated with genetic variants that alter dopamine availability.

Annals of human genetics - 1 May 2006

Need A C, Ahmadi K R, Spector T D, Goldstein D B

Abstract excerpt

Human and animal studies have implicated dopamine in appetite regulation, and family studies have shown that BMI has a strong genetic component. Dopamine availability is controlled largely by three enzymes: COMT, MAOA and MAOB, and by the dopamine transporter SLC6A3, and each gene has a well-char...

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Share to Body Mass Index
Share to Body Weight
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine

Share to Dopamine Plasma Membrane Transport Proteins

Share to Monoamine Oxidase

Share to Obesity

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16674552
DOI: 10.1111/j.1529-8817.2005.00228.x

Genes

MAOA
MAOB
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16674552-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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