Article
D4 dopamine receptor gene exon III polymorphism and obesity risk.
Eating and weight disorders : EWD - 1 Jun 1998
Poston W S, Ericsson M, Linder J, Haddock C K, Hanis C L, Nilsson T, Aström M, Foreyt J P
Abstract excerpt
Many genes have been identified that may play a role in increasing individual susceptibility to obesity. Reduced dopamine function appears to play a role in dysfunctional eating patterns and may predispose some individuals to obesity. The long version of the D4 dopamine receptor gene (D4DR) has been shown to alter receptor function and reduce intracellular response to dopamine. It also has been associated with...
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