Dopaminergic system gene polymorphisms associated with severe obesity and related outcomes: A case-control study in Brazil.

doi:10.1016/j.bbr.2026.116226

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Article

Dopaminergic system gene polymorphisms associated with severe obesity and related outcomes: A case-control study in Brazil.

Behavioural brain research - 9 Jul 2026

Teixeira Myrela Ribeiro, Felício Rafaela de Freitas Martins, Assis Izadora Sthephanie da Silva, Gouvea Laura Wendling, Abreu Gabriella Medeiros, Souza Ritiele Bastos de, Palhinha Lohanna, Junior Mario Campos, de Mello Neto Cícero Brasileiro, Maya-Monteiro Clarissa Menezes, Bozza Patrícia Torres, Carneiro João Regis Ivar, Zembrzuski Verônica Marques, Salum Kaio Cezar Rodrigues, da Fonseca Ana Carolina Proença, Kohlrausch Fabiana Barzotto

Abstract excerpt

PURPOSE: Obesity has been increasing at an uncontrolled rate. Genetic variations have been shown to contribute to a higher risk of developing the condition, due to impaired satiety regulation, predisposition to addictive eating behaviors, or even specific personality traits. This study aimed to evaluate the influence of gene polymorphisms related to the dopaminergic system on developing severe obesity. METHODS: A...

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Identifiers

PMID: 41999777
DOI: 10.1016/j.bbr.2026.116226

Genes

DRD2
COMT

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