Negative control of heavy metal uptake by the Saccharomyces cerevisiae BSD2 gene.

doi:10.1074/jbc.272.18.11763

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Article

Negative control of heavy metal uptake by the Saccharomyces cerevisiae BSD2 gene.

The Journal of biological chemistry - 2 May 1997

Liu X F, Supek F, Nelson N, Culotta V C

Abstract excerpt

We have previously shown that mutations in the Saccharomyces cerevisiae BSD2 gene suppress oxidative damage in cells lacking superoxide dismutase and also lead to hyperaccumulation of copper ions. We demonstrate here that bsd2 mutant cells additionally accumulate high levels of cadmium and cobalt...

Topics

Cadmium
Cobalt
Culture Media
Gene Deletion
Genes, Fungal
Genotype
Kinetics
Metals, Heavy
Oxidative Stress
Saccharomyces cerevisiae
Superoxide Dismutase
Suppression, Genetic

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