Article
The natural somatic mutation frequency and human carcinogenesis.
Advances in cancer research - 1 Jan 1997
Simpson A J
Abstract excerpt
Much recent attention has been paid to the important role of the DNA mismatch repair system in controlling the accumulation of somatic mutations in human tissues and the association of mismatch repair deficiency with carcinogenesis. In the absence of an intact mismatch repair system, cells accumu...
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