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Article

Multiple roles for the Wilms' tumour suppressor gene, WT1 in genitourinary development.

Molecular and cellular endocrinology - 25 May 1998

Schedl A, Hastie N

Abstract excerpt

Wilms' tumour is a childhood kidney cancer, and a classic example of cancer arising through disrupted development (Armstrong et al., 1992). It is one of the most common solid paediatric malignancies, affecting one in 10000 children. The genetics of Wilms' tumour is complicated, with several different genes or chromosomal regions being implicated (Armstrong et al., 1992). However, the gene we know most about is...

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PMID: 9722170
DOI: 10.1016/s0303-7207(98)00031-8

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Multiple roles for the Wilms' tumour suppressor gene, WT1 in genitourinary development.PMID 9722170Read ↗

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The genetic factors contributing to the development of Wilm's tumor and their clinical utility in its diagnosis and prognosis.Semantic proximity Read ↗

Exploring the Multifaceted Role of WT1 in Kidney Development and DiseaseSemantic proximity Read ↗

WT1: a novel tumor suppressor gene inactivated in Wilms' tumor.Semantic proximity Read ↗

Wilms' tumor gene 1: lessons from the interface between kidney development and cancer.Semantic proximity Read ↗

Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice.Semantic proximity Read ↗

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