Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different female reproductive phenotypes determined by human growth hormone (hGH) levels in hGH-transgenic rats.

Biology of reproduction - 1 Apr 1997

Ikeda A, Matsumoto Y, Chang K T, Nakano T, Matsuyama S, Yamanouchi K, Ohta A, Nishihara M, Tojo H, Sasaki F, Takahashi M

Abstract excerpt

The effect of continuous human GH (hGH) secretion on female reproduction was studied in adult female transgenic rats expressing the hGH gene with a mouse whey acidic protein (mWAP) promoter. Two lines of transgenic female rats carrying the mWAP/hGH gene were established and used in the study. One was characterized by relatively high levels of serum hGH (high line), and the other had relatively low levels (low...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Promoter Regions, Genetic

Share to Rats, Wistar

Share to Recombinant Fusion Proteins

Source

Identifiers

PMID: 9096864
DOI: 10.1095/biolreprod56.4.847

Genes

PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different female reproductive phenotypes determined by human growth hormone (hGH) levels in hGH-transgenic rats.PMID 9096864Read ↗

Fertility of transgenic female mice expressing bovine growth hormone or human growth hormone variant genes.Semantic proximity Read ↗

Neuroendocrine and Reproductive Consequences of Overexpression of Growth Hormone in Transgenic MiceSemantic proximity Read ↗

Effects of expression of human or bovine growth hormone genes on sperm production and male reproductive performance in four lines of transgenic mice.Semantic proximity Read ↗

Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice.Semantic proximity Read ↗

Short-term pharmacological suppression of the hyperprolactinemia of infertile hCG-overproducing female mice persistently restores their fertility.Semantic proximity Read ↗

The pleiotropic effects of excessive luteinizing hormone secretion in transgenic mice.Semantic proximity Read ↗

Infertility in a line of mice with the high growth mutation is due to luteal insufficiency resulting from disruption at the hypothalamic-pituitary axis.Semantic proximity Read ↗

Fetal but not adult Leydig cells are susceptible to adenoma formation in response to persistently high hCG level: a study on hCG overexpressing transgenic mice.Semantic proximity Read ↗

Ovarian hyperstimulation by LH leads to mammary gland hyperplasia and cancer predisposition in transgenic mice.Semantic proximity Read ↗

Completely humanizing prolactin rescues infertility in prolactin knockout mice and leads to human prolactin expression in extrapituitary mouse tissues.Semantic proximity Read ↗

Effects of heterologous growth hormones on hypothalamic and pituitary function in transgenic mice.Semantic proximity Read ↗

The Human Growth Hormone Gene Cluster Locus Control Region Supports Position-independent Pituitary- and Placenta-specific Expression in the Transgenic MouseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.