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Article

Effects of heterologous growth hormones on hypothalamic and pituitary function in transgenic mice.

Neuroendocrinology - 1 Apr 1991

Steger R W, Bartke A, Parkening T A, Collins T, Buonomo F C, Tang K C, Wagner T E, Yun J S

Abstract excerpt

The expression of the mouse metallothionein-I (mMT) promoter/human growth hormone (hGH) fusion gene in transgenic mice leads to female sterility and major alterations in the function of the hypothalamic-adenohypophyseal system. These alterations include increases in median-eminence norepinephrine turnover and plasma LH levels, and a decrease in plasma prolactin levels in intact males, and an increase in...

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Identifiers

PMID: 2046870
DOI: 10.1159/000125743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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