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Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1

1 May 1997

Abstract excerpt

The condition of a chimpanzee (C499) infected with three different isolates of human immunodeficiency virus type 1 (HIV-1) for over 10 years progressed to AIDS. Disease development in this animal was characterized by (i) a decline in CD4+ cells over the last 3 years; (ii) an increase in viral loads in plasma; (iii) the presence of a virus, termed HIV-1JC, which is cytopathic for chimpanzee peripheral blood...

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Identifiers

PMID: 9094687
DOI: 10.1128/jvi.71.5.4086-4091.1997

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