Role of basic residues in the subgroup-determining region of the subgroup A avian sarcoma and leukosis virus envelope in receptor binding and infection.

doi:10.1128/JVI.71.5.3458-3465.1997

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Article

Role of basic residues in the subgroup-determining region of the subgroup A avian sarcoma and leukosis virus envelope in receptor binding and infection.

Journal of virology - 1 May 1997

Rong L, Edinger A, Bates P

Abstract excerpt

Receptor specificity in avian sarcoma and leukosis viruses (ASLV) maps to the central region of the envelope surface protein, SU. Two hypervariable regions, hr1 and hr2, within this region of SU are the principal determinants of receptor specificity. The cellular receptor for subgroup A ASLV, Tva...

Topics

Alpharetrovirus
Amino Acid Sequence
Binding Sites
Molecular Sequence Data
Mutation
Receptors, Virus
Viral Envelope Proteins

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