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Article

Intronic deletions that disrupt mRNA splicing of the tva receptor gene result in decreased susceptibility to infection by avian sarcoma and leukosis virus subgroup A.

Journal of virology - 1 Feb 2012

Reinišová Markéta, Plachý Jiří, Trejbalová Kateřina, Šenigl Filip, Kučerová Dana, Geryk Josef, Svoboda Jan, Hejnar Jiří

Abstract excerpt

The group of closely related avian sarcoma and leukosis viruses (ASLVs) evolved from a common ancestor into multiple subgroups, A to J, with differential host range among galliform species and chicken lines. These subgroups differ in variable parts of their envelope glycoproteins, the major determinants of virus interaction with specific receptor molecules. Three genetic loci, tva, tvb, and tvc, code for single...

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Identifiers

PMID: 22171251
DOI: 10.1128/JVI.05771-11
PMCID: PMC3302400

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Intronic deletions that disrupt mRNA splicing of the tva receptor gene result in decreased susceptibility to infection by avian sarcoma and leukosis virus subgroup A.PMID 22171251Read ↗

Intronic deletions of tva receptor gene decrease the susceptibility to infection by avian sarcoma and leukosis virus subgroup A.Semantic proximity Read ↗

Two different molecular defects in the Tva receptor gene explain the resistance of two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses.Semantic proximity Read ↗

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