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Article

Importance of cysteines in the LDLR-related domain of the subgroup A avian leukosis and sarcoma virus receptor for viral entry.

Journal of virology - 1 Feb 1995

Bélanger C, Zingler K, Young J A

Abstract excerpt

The extracellular domain of the subgroup A avian sarcoma and leukemia virus (ALSV-A) receptor contains a region that is related in sequence to the ligand-binding motifs of the low-density lipoprotein receptor (LDLR). This domain contains six cysteines that are highly conserved between different members of the LDLR protein superfamily, and these residues are presumed to participate in intrachain disulfide bonds....

Topics

Alpharetrovirus
Amino Acid Sequence
Animals
Base Sequence
Cell Line
Chick Embryo
Cysteine
Molecular Sequence Data
Mutation
Receptors, LDL
Receptors, Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Structure-Activity Relationship

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Open in PubMed Open full text

Identifiers

PMID: 7815478
DOI: 10.1128/JVI.69.2.1019-1024.1995
PMCID: PMC188671

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7815478-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Importance of cysteines in the LDLR-related domain of the subgroup A avian leukosis and sarcoma virus receptor for viral entry.PMID 7815478Read ↗

Role of basic residues in the subgroup-determining region of the subgroup A avian sarcoma and leukosis virus envelope in receptor binding and infection.Semantic proximity Read ↗

Two different molecular defects in the Tva receptor gene explain the resistance of two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses.Semantic proximity Read ↗

Identification and characterization of a shared TNFR-related receptor for subgroup B, D, and E avian leukosis viruses reveal cysteine residues required specifically for subgroup E viral entry.Semantic proximity Read ↗

Characterization of the LDL-A module mutants of Tva, the subgroup A Rous sarcoma virus receptor, and the implications in protein folding.Semantic proximity Read ↗

Mutational analysis of the subgroup A avian sarcoma and leukosis virus putative fusion peptide domain.Semantic proximity Read ↗

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