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Article

[Amyotrophic lateral sclerosis and superoxide dismutase--a review].

Ugeskrift for laeger - 10 Mar 1997

Binzer M N, Gredal O, Brøndum-Nielsen K, Andersen P M

Abstract excerpt

The recent observation that mutations in cytosolic CuZn-superoxide dismutase (CuZn-SOD) are associated with amyotrophic lateral sclerosis (ALS) suggests that the disease arises from a perturbation of the homeostasis of free radicals resulting in neuronal degeneration by reactive oxygen species. The stability is altered in these mutant molecules, but without necessarily reducing the specific activity of the...

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PMID: 9092140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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