Article
Detection of variants in the mitochondrial glycerophosphate dehydrogenase gene in Japanese NIDDM patients.
Diabetologia - 1 Mar 1997
Takeuchi Y, Matsutani A, Oka Y
Abstract excerpt
Mitochondrial FAD-linked glycerophosphate dehydrogenase (mGPDH) is thought to be an important factor for glucose sensing in pancreatic beta cells. To evaluate the significance of the mGPDH gene in the development of non-insulin-dependent diabetes mellitus (NIDDM), we set up primers and conditions...
Topics
- Amino Acid Sequence
- Base Sequence
- Codon
- DNA Primers
- Diabetes Mellitus, Type 2
- Exons
- Female
- Gene Frequency
- Genetic Variation
- Genotype
- Glycerolphosphate Dehydrogenase
- Humans
- Japan
- Male
- Middle Aged
- Mitochondria
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational