Article
Comparison of activation requirements and activation phenotype of allogeneic and xenogeneic rodent responses in vivo and in vitro.
Transplantation - 15 Aug 2001
Trani J L, Song H K, Lerner S M, Markmann J W, Barker C F, Naji A, Markmann J F
Abstract excerpt
BACKGROUND: Both discordant and concordant xenogeneic responses are dominated by humoral immunity. Recent advances in molecular engineering approaches may largely prevent rejection by means of this pathway, leaving the cellular arm of the immune response as the principal remaining barrier to successful engraftment. METHODS: To characterize further the cellular response to xenogeneic tissues, we used the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.