Article
A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2002
Liloglou Triantafillos, Walters Matthew, Maloney Paul, Youngson Judith, Field John K
Abstract excerpt
The human Mu class Glutathione S-Transferases is a family of genes encoding phase II detoxifying enzymes thus playing a significant role in the detoxification of potential carcinogens. While there are many contradicting reports on the association of GSTM1 polymorphisms and cancer development, no studies exist to date describing polymorphisms in GSTM4. We have identified a new C-T polymorphism in intron 6 of the...
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