Article
Lung cancer risk of GSTM1 null genotype is dependent on the extent of tobacco smoke exposure.
Carcinogenesis - 1 Feb 1994
Kihara M, Kihara M, Noda K
Abstract excerpt
Recently, homozygous gene deletion of GSTM1, one of the Mu class glutathione S-transferase isozymes, was found to occur in approximately half of the population of various ethnic origins and has been implicated in tobacco-related carcinogenesis. In the present study we evaluated the risk of GSTM1 null genotype for lung cancer in relation to the extent of tobacco smoke exposure in 178 lung cancer patients (157...
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