Lung cancer risk of GSTM1 null genotype is dependent on the extent of tobacco smoke exposure.

doi:10.1093/carcin/15.2.415

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Article

Lung cancer risk of GSTM1 null genotype is dependent on the extent of tobacco smoke exposure.

Carcinogenesis - 1 Feb 1994

Kihara M, Kihara M, Noda K

Abstract excerpt

Recently, homozygous gene deletion of GSTM1, one of the Mu class glutathione S-transferase isozymes, was found to occur in approximately half of the population of various ethnic origins and has been implicated in tobacco-related carcinogenesis. In the present study we evaluated the risk of GSTM1...

Topics

Aged
Base Sequence
DNA Primers
Female
Genotype
Glutathione Transferase
Humans
Lung Neoplasms
Male
Molecular Sequence Data
Risk Factors
Smoking

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