Article
Can't lung cancer patients detoxify procarcinogens?
Allergie et immunologie - 1 Feb 2002
Cerrahoglu K, Kunter E, Isitmangil T, Oztosun A I M, Isitmangil G, Okutan O, Bozkanat E, Aydilek R, Bener A
Abstract excerpt
BACKGROUND: Glutathione S-transferase mu (GST mu) enzyme detoxifies carcinogens in tobacco smoke. We assessed the clinical usefulness of serum assay of GSTm in determining the risk for lung cancer. MATERIALS AND METHODS: Fifty-nine patients with primary lung cancer and 32 control cases were enrolled. GSTm detection was performed by the method ELISA. RESULTS: GSTm enzyme positivity rate of the patient group (39%)...
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