Article
Identification of sequence alterations in the upstream regulatory region of the estrogen receptor gene in an ER-negative breast cancer cell line.
Cancer letters - 26 Feb 1997
Sullivan J A, Cohn C S, Hill S M
Abstract excerpt
Given the important role of the estrogen receptor (ER) in the development and physiology of the breast, it is essential to delineate the mechanisms responsible for its failed expression in some breast tumors. We have cloned and sequenced a portion of the ER upstream regulatory region from the ER-...
Topics
- Base Sequence
- Breast Neoplasms
- Chloramphenicol O-Acetyltransferase
- Cloning, Molecular
- Female
- Genetic Variation
- Humans
- Leukocytes
- Molecular Sequence Data
- Receptors, Estrogen
- Regulatory Sequences, Nucleic Acid
- Sequence Homology, Nucleic Acid
- Tumor Cells, Cultured