A role for naturally occurring variation of the murine coronavirus spike protein in stabilizing association with the cellular receptor.

doi:10.1128/JVI.71.4.3129-3137.1997

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Article

A role for naturally occurring variation of the murine coronavirus spike protein in stabilizing association with the cellular receptor.

Journal of virology - 1 Apr 1997

Gallagher T M

Abstract excerpt

Murine hepatitis virus (MHV), a coronavirus, initiates infection by binding to its cellular receptor (MHVR) via spike (S) proteins projecting from the virion membrane. The structures of these S proteins vary considerably among MHV strains, and this variation is generally considered to be importan...

Topics

Animals
Cell Adhesion Molecules
Cell Line
Evolution, Molecular
Genetic Variation
Glycoproteins
HeLa Cells
Humans
Immunoglobulin Fc Fragments
Immunoglobulin G
Membrane Glycoproteins
Mice
Murine hepatitis virus
Receptors, Virus
Recombinant Fusion Proteins
Species Specificity
Spike Glycoprotein, Coronavirus
Temperature

Source

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Identifiers

PMID: 9060676
DOI: 10.1128/JVI.71.4.3129-3137.1997
PMCID: PMC191445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9060676-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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