Article
Human ACE gene polymorphism and distilled water induced cough.
Thorax - 1 Feb 1997
Morice A H, Turley A J, Linton T K
Abstract excerpt
BACKGROUND: Inhibitors of angiotensin converting enzyme (ACE) cause a non-productive cough. The insertion/deletion polymorphism of ACE was used as a genetic marker to investigate the relationship between ACE genotype and cough sensitivity. METHODS: A double blind cough challenge was performed in 66 normotensive subjects (34 men) of mean age 34.8 years (range 18-80) using aerosols of distilled water. The number of...
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