Article
Is there an association between angiotensin-converting enzyme gene variants and chronic nonproductive cough?
Chest - 1 Oct 2000
McGarvey L P, Savage D A, Feeney S A, Heaney L G, Ennis M, MacMahon J, Maxwell A P
Abstract excerpt
BACKGROUND: It is unclear why some patients develop a chronic nonproductive cough. Angiotensin-converting enzyme (ACE) inactivates tussive peptides in the airways such as bradykinin and tachykinins. An insertion/deletion polymorphism in the ACE gene accounts for variation in ACE levels, and patie...
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