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Article

Bradykinin B(2) receptor gene polymorphism is associated with angiotensin-converting enzyme inhibitor-related cough.

Hypertension (Dallas, Tex. : 1979) - 1 Jul 2000

Mukae S, Aoki S, Itoh S, Iwata T, Ueda H, Katagiri T

Abstract excerpt

The appearance of cough in association with angiotensin-converting enzyme (ACE) inhibitors is thought to be related to bradykinin, and it has been speculated that the elicitation of adverse effects is genetically predetermined. Several polymorphisms of the human bradykinin B(2) receptor gene may be involved in ACE inhibitor-related cough. To investigate this possibility, we identified the -58 thymine (T)/cytosine...

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Source

Identifiers

PMID: 10904024
DOI: 10.1161/01.hyp.36.1.127

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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