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Article

Deletion allele of the angiotensin-converting enzyme gene as a risk factor for pneumonia in elderly patients.

The American journal of medicine - 1 Feb 2002

Morimoto Shigeto, Okaishi Kohya, Onishi Miyuki, Katsuya Tomohiro, Yang Jin, Okuro Masashi, Sakurai Shoroku, Onishi Toshio, Ogihara Toshio

Abstract excerpt

PURPOSE: Aspiration due to an age-related reduction in cough is a major cause of pneumonia in elderly persons. Because the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene (ACE) has been associated with the cough reflex, we studied whether this genetic polymorphism was also associated with the risk of pneumonia. SUBJECTS AND METHODS: We studied 1011 elderly inpatients (221 men...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11835945
DOI: 10.1016/s0002-9343(01)01071-3

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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