Article
The ACE gene polymorphism and cough threshold for capsaicin after cilazapril usage.
Respiratory medicine - 1 Feb 2001
Takahashi T, Yamaguchi E, Furuya K, Kawakami Y
Abstract excerpt
Persistent dry cough is an occasional but clinically important adverse reaction to angiotensin I-converting enzyme (ACE) inhibitors (ACEI). Its reported incidence is variable, and why cough occurs in only certain individuals has been unclear. An insertion/deletion (I/D) polymorphism of the ACE gene is associated with serum ACE activity. We have previously shown that susceptibility to cough induced by ACEI is...
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