Article
Temporal sequence of gene expression leading caudal prosencephalon to develop a midbrain/hindbrain phenotype.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2002
Hidalgo-Sánchez Matías, Alvarado-Mallart Rosa-Magda
Abstract excerpt
Transplantation of prosomeres 1-2 into the cerebellar plate were used, by using chick/quail chimeras, to analyse the temporal sequence of the genetic cascade leading the graft to develop a midbrain/hindbrain phenotype. Our results show that (1) at Hamburger and Hamilton (HH) stage 13, Pax2 and En2 are already induced within the graft, before all other genes of the cascade, whereas misexpression of Fgf8 is also...
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