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Article

The mechanism of fission yeast mating type interconversion: seal/replicate/cleave model of replication across the double-stranded break site at mat1.

Genetics - 1 Mar 1991

Klar A J, Bonaduce M J, Cafferkey R

Abstract excerpt

The interconversion of cell type in the fission yeast, Schizosaccharomyces pombe, is initiated by a double-stranded break (DSB) found at the mating type locus (mat1). A heritable site- and strand-specific DNA "imprinting" event at mat1 was recently hypothesized to be required to make the mat1 locus cleavable, and the DSB was suggested to be produced one generation before the actual switching event. It is known...

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Identifiers

PMID: 2016051
DOI: 10.1093/genetics/127.3.489
PMCID: PMC1204376

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