Article
The mechanism of fission yeast mating type interconversion: seal/replicate/cleave model of replication across the double-stranded break site at mat1.
Genetics - 1 Mar 1991
Klar A J, Bonaduce M J, Cafferkey R
Abstract excerpt
The interconversion of cell type in the fission yeast, Schizosaccharomyces pombe, is initiated by a double-stranded break (DSB) found at the mating type locus (mat1). A heritable site- and strand-specific DNA "imprinting" event at mat1 was recently hypothesized to be required to make the mat1 loc...
Topics
- Alleles
- Base Sequence
- Blotting, Southern
- Cloning, Molecular
- DNA Repair
- DNA Replication
- DNA, Fungal
- Gene Conversion
- Genes, Fungal
- Genes, Mating Type, Fungal
- Genes, Switch
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Schizosaccharomyces
- Spores, Fungal