Article
Ephedrine blocks wild-type and long-lived mutant acetylcholine receptor channels.
Neuroreport - 20 Dec 1996
Bouzat C
Abstract excerpt
A combination of transient expression of wild-type and a mutant muscle nicotinic receptor (AChR) found in a patient suffering from a congenital myasthenic syndrome and single-channel recordings was used to characterize the action of ephedrine on the AChR. In the presence of ephedrine, both types of AChR channel showed a flickering behaviour and a dose-dependent reduction in the mean open time. The duration of the...
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