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Article

Inherited, selective hyporesponsiveness to the analgesic action of nicotine in mice.

Neuroreport - 20 Dec 1996

Seale T W, Nael R, Basmadjian G

Abstract excerpt

The acute dose-dependent analgesic activity of nicotine, as measured by the tail-flick assay, differed significantly between CD-1 and CF-1 outbred strains of mice. Differing responsiveness to the tail-flick stimulus did not explain this pharmacological effect. The inherent analgesic hyporesponsiveness of CF-1 mice was pharmacologically selective. Xilocaine and morphine produced an analgesic response of large...

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Source

Identifiers

PMID: 9051779
DOI: 10.1097/00001756-199612200-00039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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