Article
Characterization of the genetic elements controlling lipoprotein(a) concentrations in Mexican Americans. Evidence for at least three controlling elements linked to LPA, the locus encoding apolipoprotein(a).
Atherosclerosis - 10 Feb 1997
Rainwater D L, Kammerer C M, VandeBerg J L, Hixson J E
Abstract excerpt
Analyses of 1163 samples from the San Antonio Family Heart Study revealed several elements of genetic control of lipoprotein(a) (Lp(a)) concentrations in Mexican Americans. Apolipoprotein(a) (apo(a)) isoform size variation was inversely related to Lp(a) concentrations and explained about 22% of t...
Topics
- Adult
- Apolipoproteins
- Apoprotein(a)
- Chromosome Mapping
- Female
- Genes
- Genetic Linkage
- Genetic Variation
- Humans
- Lipoprotein(a)
- Male
- Mexican Americans
- Middle Aged
- Models, Genetic
- Osmolar Concentration
- Polymorphism, Genetic
- Promoter Regions, Genetic
