Article
The apolipoprotein(a) gene: linkage disequilibria at three loci differs in African Americans and Caucasians.
Atherosclerosis - 1 Nov 2008
Rubin Jill, Kim Han Jo, Pearson Thomas A, Holleran Steve, Berglund Lars, Ramakrishnan Rajasekhar
Abstract excerpt
Lipoprotein(a) (Lp(a)) is an independent, genetically regulated cardiovascular risk factor. Lp(a) plasma levels are largely determined by the apolipoprotein(a) (apo(a)) component, and differ across ethnicity. Although a number of polymorphisms in the apo(a) gene have been identified, apo(a) genetic regulation is not fully understood. To study the relation between apo(a) gene variants, we constructed haplotypes...
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