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Article

The apolipoprotein(a) gene: linkage disequilibria at three loci differs in African Americans and Caucasians.

Atherosclerosis - 1 Nov 2008

Rubin Jill, Kim Han Jo, Pearson Thomas A, Holleran Steve, Berglund Lars, Ramakrishnan Rajasekhar

Abstract excerpt

Lipoprotein(a) (Lp(a)) is an independent, genetically regulated cardiovascular risk factor. Lp(a) plasma levels are largely determined by the apolipoprotein(a) (apo(a)) component, and differ across ethnicity. Although a number of polymorphisms in the apo(a) gene have been identified, apo(a) genetic regulation is not fully understood. To study the relation between apo(a) gene variants, we constructed haplotypes...

Topics

Black or African American
Apoprotein(a)
Atherosclerosis
Cohort Studies
Female
Gene Frequency
Genetic Loci
Genetic Predisposition to Disease
Haplotypes
Humans
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Microsatellite Repeats

Polymorphism, Genetic

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 18304554
DOI: 10.1016/j.atherosclerosis.2008.01.002
PMCID: PMC2784197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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The apolipoprotein(a) gene: linkage disequilibria at three loci differs in African Americans and Caucasians.PMID 18304554Read ↗

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