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Article

Assessment of Apolipoprotein(a) Isoform Size Using Phenotypic and Genotypic Methods.

International journal of molecular sciences - 9 Sept 2023

Fogacci Federica, Di Micoli Valentina, Avagimyan Ashot, Giovannini Marina, Imbalzano Egidio, Cicero Arrigo F G

Abstract excerpt

Apolipoprotein(a) (apo(a)) is the protein component that defines lipoprotein(a) (Lp(a)) particles and is encoded by the LPA gene. The apo(a) is extremely heterogeneous in size due to the copy number variations in the kringle-IV type 2 (KIV2) domains. In this review, we aim to discuss the role of genetics in establishing Lp(a) as a risk factor for coronary heart disease (CHD) by examining a series of molecular...

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Identifiers

PMID: 37762189
DOI: 10.3390/ijms241813886
PMCID: PMC10531419

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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