Article
Helicase motifs V and VI of the Escherichia coli UvrB protein of the UvrABC endonuclease are essential for the formation of the preincision complex.
Journal of molecular biology - 22 Jul 1994
Moolenaar G F, Visse R, Ortiz-Buysse M, Goosen N, van de Putte P
Abstract excerpt
The UvrB protein is a subunit of the UvrABC endonuclease which is involved in the repair of a large variety of DNA lesions. We have 91 isolated random uvrB mutants which are impaired in the repair of UV-damage in vivo. These mutants were classified on the basis of the ability to form normal level...
Topics
- Adenosine Triphosphate
- Bacterial Proteins
- Base Sequence
- DNA Helicases
- DNA Primers
- DNA Repair
- Endodeoxyribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Molecular Sequence Data
- Mutation