Article
The C-terminal region of Escherichia coli UvrC contributes to the flexibility of the UvrABC nucleotide excision repair system.
Nucleic acids research - 1 Jun 2002
Verhoeven Esther E A, van Kesteren Marian, Turner John J, van der Marel Gijs A, van Boom Jacques H, Moolenaar Geri F, Goosen Nora
Abstract excerpt
Nucleotide excision repair in Escherichia coli involves formation of the UvrB-DNA complex and subsequent DNA incisions on either site of the damage by UvrC. In this paper, we studied the incision of substrates with different damages in varying sequence contexts. We show that there is not always a correlation between the incision efficiency and the stability of the UvrB-DNA complex. Both stable and unstable...
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