Article
COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants.
The Journal of cell biology - 24 Feb 1997
Gaynor E C, Emr S D
Abstract excerpt
The coatomer (COPI) complex mediates Golgi to ER recycling of membrane proteins containing a dilysine retrieval motif. However, COPI was initially characterized as an anterograde-acting coat complex. To investigate the direct and primary role(s) of COPI in ER/Golgi transport and in the secretory pathway in general, we used PCR-based mutagenesis to generate new temperature-conditional mutant alleles of one COPI...
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