Article
A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1.
Molecular and cellular biology - 1 Dec 1998
Chen E J, Frand A R, Chitouras E, Kaiser C A
Abstract excerpt
Secretory proteins in eukaryotic cells are transported to the cell surface via the endoplasmic reticulum (ER) and the Golgi apparatus by membrane-bounded vesicles. We screened a collection of temperature-sensitive mutants of Saccharomyces cerevisiae for defects in ER-to-Golgi transport. Two of th...
Topics
- Alleles
- Amino Acid Sequence
- Conserved Sequence
- DEAD-box RNA Helicases
- Fungal Proteins
- GTP-Binding Proteins
- Genes, Fungal
- Genes, Reporter
- Glycoside Hydrolases
- Glycosylation
- Molecular Sequence Data
- Monomeric GTP-Binding Proteins
- Mutation
- RNA Precursors
- RNA Processing, Post-Transcriptional