Na(+)-H+ antiporter phenotype, abundance, and phosphorylation of immortalized lymphoblasts from humans with hypertension.

doi:10.1161/01.hyp.25.5.971

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Article

Na(+)-H+ antiporter phenotype, abundance, and phosphorylation of immortalized lymphoblasts from humans with hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 May 1995

Ng L L, Sweeney F P, Siczkowski M, Davies J E, Quinn P A, Krolewski B, Krolewski A S

Abstract excerpt

Previous studies have demonstrated an elevated Na(+)-H+ exchanger activity in various cell types from patients with essential hypertension. The phenotype of an increased maximal transport capacity is preserved in Epstein-Barr virus immortalized lymphoblasts from hypertensive patients. The mechani...

Topics

Adult
Cells, Cultured
Female
Humans
Hydrogen-Ion Concentration
Hypertension
Lymphocytes
Male
Middle Aged
Phenotype
Phosphorylation
Sodium-Hydrogen Exchangers

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