Adaptive mutation in Escherichia coli: a role for conjugation.

doi:10.1126/science.7716545

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Article

Adaptive mutation in Escherichia coli: a role for conjugation.

Science (New York, N.Y.) - 21 Apr 1995

Radicella J P, Park P U, Fox M S

Abstract excerpt

When subjected to selective conditions that impose starvation, a bacterial population can accumulate mutations, called adaptive, that allow colony formation. Here, the reversion of a lac allele under selective conditions, in a model system using Escherichia coli with the lac mutation on an F' pla...

Topics

Adaptation, Physiological
Alleles
Bacterial Proteins
Conjugation, Genetic
Culture Media
DNA Replication
Escherichia coli
Escherichia coli Proteins
F Factor
Frameshift Mutation
Lac Operon
Lac Repressors
Lactose
Mutation
Repressor Proteins
Selection, Genetic

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