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Article

The DFer gene of Drosophila melanogaster encodes two membrane-associated proteins that can both transform vertebrate cells.

Oncogene - 13 Feb 1997

Paulson R, Jackson J, Immergluck K, Bishop J M

Abstract excerpt

The vertebrate gene FER encodes two protein-tyrosine kinases with molecular weights of 51,000 and 94,000 and distinctive aminotermini. The larger kinase is expressed ubiquitously among vertebrate tissues, whereas expression of the smaller kinase appears to be limited to spermatogenic cells in the...

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PMID: 9038371
DOI: 10.1038/sj.onc.1200875

Genes

FER
SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9038371-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The DFer gene of Drosophila melanogaster encodes two membrane-associated proteins that can both transform vertebrate cells.PMID 9038371Read ↗

Expression of Fer testis (FerT) tyrosine kinase transcript variants and distribution sites of FerT during the development of the acrosome-acroplaxome-manchette complex in rat spermatids.Semantic proximity Read ↗

The Fes/Fer non-receptor tyrosine kinase cooperates with Src42A to regulate dorsal closure in Drosophila.Semantic proximity Read ↗

Mice devoid of fer protein-tyrosine kinase activity are viable and fertile but display reduced cortactin phosphorylation.Semantic proximity Read ↗

Phosphorylation status of the Kep1 protein alters its affinity for its protein binding partner alternative splicing factor ASF/SF2.Semantic proximity Read ↗

Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line.Semantic proximity Read ↗

The FERONIA receptor-like kinase mediates male-female interactions during pollen tube reception.Semantic proximity Read ↗

Characterization of Drosophila GDNF receptor-like and evidence for its evolutionarily conserved interaction with neural cell adhesion molecule (NCAM)/FasII.Semantic proximity Read ↗

E2F-dependent transcription of the raf proto-oncogene during Drosophila development.Semantic proximity Read ↗

Direct binding of plectin to Fer kinase and negative regulation of its catalytic activity.Semantic proximity Read ↗

Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences.Semantic proximity Read ↗

Continuous association of cadherin with beta-catenin requires the non-receptor tyrosine-kinase Fer.Semantic proximity Read ↗

Activated T cells express a novel gene on chromosome 8 that is closely related to the murine ecotropic retroviral receptor.Semantic proximity Read ↗

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