Article
Activated T cells express a novel gene on chromosome 8 that is closely related to the murine ecotropic retroviral receptor.
Molecular and cellular biology - 1 Jul 1990
MacLeod C L, Finley K, Kakuda D, Kozak C A, Wilkinson M F
Abstract excerpt
A novel cDNA clone (20.5) which is differentially expressed between two closely related T-lymphoma cell clones was isolated by subtraction-enriched differential screening. SL12.4 cells, from which the cDNA was isolated, have characteristics of thymocytes at an intermediate stage in development. A sister cell clone derived from the same tumor, SL12.3, does not express this mRNA, has a distinct phenotype, and...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Cells, Cultured
- Chromosomes, Human, Pair 8
- DNA
- Gene Library
- Genes
- Humans
- Lymphocyte Activation
