Article
Screening the monoamine oxidase B gene in 100 male patients with schizophrenia: a cluster of polymorphisms in African-Americans but lack of functionally significant sequence changes.
American journal of medical genetics - 21 Feb 1997
Sobell J L, Lind T J, Hebrink D D, Heston L L, Sommer S S
Abstract excerpt
The monoamine oxidase B (MAO-B) gene was examined in 100 alleles derived from 80 Caucasian, 10 African-American, 5 Asian, and 5 Native American male patients with schizophrenia to identify sequence changes that might be associated with the disease. Approximately 235 kb of genomic sequence, primar...
Topics
- Black People
- DNA Primers
- Genetic Linkage
- Genetic Markers
- Humans
- Indians, North American
- Male
- Monoamine Oxidase
- Mutation
- Polymorphism, Genetic
- Polymorphism, Single-Stranded Conformational
- Schizophrenia
- Sequence Analysis
- Sex Chromosomes