Article
Association between monoamine oxidase (MAO)-A gene variants and schizophrenia in a Chinese population.
Brain research - 1 Sept 2009
Qiu Hai Tang, Meng Hua Qing, Song Cai, Xiu Mei Hong, Chen Da Chun, Zhu Feng Yan, Wu Gui Ying, Kosten Therese A, Kosten Thomas R, Zhang Xiang Yang
Abstract excerpt
Monoamine oxidase (MAO) A is a critical enzyme in the catabolism of dopamine. Dysfunction of dopaminergic systems has been implicated in the pathophysiology of schizophrenia, suggesting that MAOA gene variation might be associated with the disorder. MAOA gene variation was compared between 234 Chinese schizophrenic patients and 121 healthy controls. Three polymorphic markers of the MAOA gene were analyzed using...
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