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Article

Mutational analysis of the human MAOA gene.

American journal of medical genetics - 16 Feb 1996

Tivol E A, Shalish C, Schuback D E, Hsu Y P, Breakefield X O

Abstract excerpt

The monoamine oxidases (MAO-A and MAO-B) are the enzymes primarily responsible for the degradation of amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. Wide variations in activity of these isozymes have been reported in control humans. The MAOA and MAOB genes are located next to each other in the p11.3-11.4 region of the human X chromosome. Our recent documentation of an MAO-A-deficiency...

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Source

Identifiers

PMID: 8678123
DOI: 10.1002/(SICI)1096-8628(19960216)67:1<92::AID-AJMG16>3.0.CO;2-K

Genes

MAOA
MAOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of the human MAOA gene.PMID 8678123Read ↗

Analysis of MAOA mutations in humans.Semantic proximity Read ↗

Structure of the human gene for monoamine oxidase type A.Semantic proximity Read ↗

Characterization of a highly polymorphic region near the first exon of the human MAOA gene containing a GT dinucleotide and a novel VNTR motif.Semantic proximity Read ↗

20 ans après: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition.Semantic proximity Read ↗

A functional polymorphism in the monoamine oxidase A gene promoter.Semantic proximity Read ↗

Deletion of MAOA and MAOB in a male patient causes severe developmental delay, intermittent hypotonia and stereotypical hand movementsSemantic proximity Read ↗

Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A.Semantic proximity Read ↗

DNA sequence analysis of monoamine oxidase B gene coding and promoter regions in Parkinson's disease cases and unrelated controls.Semantic proximity Read ↗

A functional polymorphism in the MAOA gene promoter (MAOA-LPR) predicts central dopamine function and body mass index.Semantic proximity Read ↗

Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoterSemantic proximity Read ↗

Screening the monoamine oxidase B gene in 100 male patients with schizophrenia: a cluster of polymorphisms in African-Americans but lack of functionally significant sequence changes.Semantic proximity Read ↗

MONOAMINE OXIDASE: From Genes to BehaviorSemantic proximity Read ↗

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