Article
Mutational analysis of candidate genes in psychiatric disorders.
American journal of medical genetics - 15 Dec 1993
Gejman P V, Gelernte J
Abstract excerpt
A genetic hypothesis for a disease presupposes the existence of variation in the DNA sequences of affected individuals. A series of techniques known together as "mutational analysis" can be applied towards identifying new sequence variations in selected genes. These techniques can screen a large series of individuals for mutations efficiently, so it is not necessary to determine the nucleotide sequence in every...
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