Article
Association study between schizophrenia and monoamine oxidase A and B DNA polymorphisms.
Psychiatry research - 1 Jun 1996
Coron B, Campion D, Thibaut F, Dollfus S, Preterre P, Langlois S, Vasse T, Moreau V, Martin C, Charbonnier F, Laurent C, Mallet J, Petit M, Frebourg T
Abstract excerpt
Monoamine oxidases (MAO) A and B, which are encoded by two distinct genes located on the human X chromosome, are both involved in the oxidative metabolism of dopamine. Decreased levels of platelet MAO-B activity has been reported in patients with schizophrenia and genetic variation in MAO activity had been proposed as a significant factor in the etiology of this disease. We carried out an association study using...
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