Article
Nucleotide and amino acid mutations in human immunodeficiency virus corresponding to CD4+ decline.
Archives of virology - 1 Jun 2006
Hill M D, Hernández W
Abstract excerpt
In a meta-analysis, gene sequences of the HIV-1 V3 and surrounding envelope region from studies examining longitudinally derived blood and plasma human immunodeficiency virus forms were analyzed for changes over disease course. CD4+ counts were used as a marker of disease progression; 58 subjects, followed an average of 56 months, were included. Genetic diversification was found early in disease progression. In...
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