Article
Disease progression and evolution of the HIV-1 env gene in 24 infected infants.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2008
Carvajal-Rodríguez Antonio, Posada David, Pérez-Losada Marcos, Keller Emily, Abrams Elaine J, Viscidi Raphael P, Crandall Keith A
Abstract excerpt
We have studied the relationship between disease progression and HIV-1 evolution in 24 infants classified as rapid or non-rapid progressors, during nearly the entire disease progression cycle from infection to AIDS. Specifically, we examined the temporal relationship between clinical status and changes in genetic diversity, divergence, selection and recombination at the C2V3C3 region of the env gene during a...
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